| Fluid | Material | ||||
| Neoprene (CR) | Nitrile (NBR) | Fluoroelastomer (FKM) | Ethylenepropylene (EPDM) | Perfluoroelastomer (FFKM) | |
| Acetic Acid (30%) | B | C | C | A | A |
| Acetone | C | C | C | A | A |
| Air, Ambient | A | A | A | A | A |
| Air, Hot (2000F (930C)) | C | B | A | A | A |
| Alcohol (Ethyl) | A | C | C | A | A |
| Alcohol (Methyl) | A | A | C | A | A |
| Ammonia (Anhydrous) (Cold) | A | A | C | A | A |
| Ammonia (Gas, Hot) | B | C | C | B | A |
| Beer | A | A | A | A | A |
| Benzene | C | C | B | C | A |
| Brine (Calcium Chloride) | A | A | B | A | A |
| Butadiene Gas | C | C | B | C | A |
| Butane (Gas) | A | A | A | C | A |
| Butane (Liquid) | C | A | A | C | A |
| Carbon Tetrachloride | C | C | A | C | A |
| Chlorine (Dry) | C | C | A | C | A |
| Chlorine (Wet) | C | C | B | C | A |
| Coke Oven Gas | C | C | A | C | A |
| Ethyl Acetate | C | C | C | B | A |
| Ethylene Glycol | A | A | A | A | A |
| Freon 11 | C | B | A | C | A |
| Freon 12 | A | A | B | B | A |
| Freon 22 | A | C | C | A | A |
| Freon 114 | A | A | B | A | A |
| Gasoline (Automotive) | C | B | A | C | A |
| Hydrogen Gas | A | A | A | A | A |
| Hydrogen Sulfide (Dry) | A | A(1) | C | A | A |
| Hydrogen Sulfide (Wet) | B | C | C | A | A |
| Jet Fuel (JP-4) | B | A | A | C | A |
| Methyl Ethyl Ketone (MEK) | C | C | C | A | A |
| MTBE | C | C | C | C | A |
| Natural Gas | A | A | A | C | A |
| Nitric Acid (50 to 100%) | C | C | B | C | A |
| Nitrogen | A | A | A | A | A |
| Oil (Fuel) | C | A | A | C | A |
| Propane | B | A | A | C | A |
| Sulfur Dioxide | A | C | A | A | A |
| Sulfuric Acid (up to 50%) | B | C | A | A | A |
| Sulfuric Acid (50 to 100%) | C | C | A | A | A |
| Water (Ambient) | A | A | A | A | A |
| Water (at 2000F (930C)) | C | B | B | B | A |
| 1- Performance worsens with hot temperatures, A - Recommended, B - Minor to moderate effect. Proceed with caution, C-Unsatisfactory, N/A - Information not available | |||||